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Immunomodulatory functional foods and their molecular mechanisms

  • 작성자

    Sanguine Byun
  • 작성일자

    2022-03-24
  • 조회수

    329
Sanguine Byun( sanguine@yonsei.ac.kr )
2020-present Assistant Professor, Department of Biotechnology, Yonsei University, South Korea
2016-2020 Assistant Professor, Division of Bioengineering, Incheon National University, South Korea
2012-2016 Postdoctoral Research Fellow, Harvard Medical School and Massachusetts General Hospital, USA
2009-2012 Ph.D., Agricultural Biotechnology, Seoul National University, South Korea
2007-2009 M.S., Agricultural Biotechnology, Seoul National University, South Korea
2000-2007 B.S., Food Science and Biotechnology / Biology, Seoul National University, South Korea

Immunomodulatory functional foods and their molecular mechanisms

The immune system comprises a complex group of processes that provide defense against diverse pathogens. These defenses can be divided into innate and adaptive immunity, in which specific immune components converge to limit infections. In addition to genetic factors, aging, lifestyle, and environmental factors can influence immune function, potentially affecting the susceptibility of the host to disease-causing agents. Chemical compounds in certain foods have been shown to regulate signal transduction and cell phenotypes, ultimately impacting pathophysiology. Research has shown that the consumption of specific functional foods can stimulate the activity of immune cells, providing protection against cancer, viruses, and bacteria. Here, we review a number of functional foods reported to strengthen immunity, including ginseng, mushrooms, chlorella, and probiotics (Lactobacillus plantarum). We also discuss the molecular mechanisms involved in regulating the activity of various types of immune cells. Identifying immune-enhancing functional foods and understanding their mechanisms of action will support new approaches to maintain proper health and combat immunological diseases.

Exp Mol Med. 2022 Jan;54(1):1-11. doi: 10.1038/s12276-022-00724-0
https://pubmed.ncbi.nlm.nih.gov/35079119