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BMB Reports

Development of bioinformatics and multi-omics analyses in organoids

  • 작성자

    Sanguk Kim
  • 작성일자

    2022-12-22
  • 조회수

    848
Name: Sanguk Kim ( sukim@postech.ac.kr )
2014-present Professor, Department of Life Sciences, POSTECH, Korea
2009-2014 Associate professor, Department of Life Sciences, POSTECH, Korea
2005-2009 Assistant professor, Department of Life Sciences, POSTECH, Korea
2002-2005 Postdoctoral research fellow, UCLA, USA
1998-2002 Ph.D., Institute of Molecular Biophysics, Florida State Univ, USA
1996-1998 Researcher, Korea Institute of Science and Technology, Korea

Development of bioinformatics and multi-omics analyses in organoids

Preclinical models are critical in gaining mechanistic and biological insights of disease progression. Recently, patient-derived organoid models have been developed to facilitate our understanding of disease development and to improve the discovery of therapeutic options by faithfully recapitulate in vivo tissue or organ. As technological developments of organoid models are rapidly growing, computational methods are gaining attention in organoid researchers to improve the ability to systematically analyze the experimental results. In this review, we summarize recent advances in organoid models to recapitulate human diseases and computational advancements to analyze experimental results from organoids.


BMB Rep. 2022 Oct 26;5744. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/36284440/