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BMB Reports

Current status and prospects of the organoid based regenerative medicine

  • 작성자

    Jongman Yoo
  • 작성일자

    2022-12-22
  • 조회수

    943
Name: Jongman Yoo ( jongmanyoo@cha.ac.kr )
2020~present Associate Professor, School of Medicine, CHA University, Korea
2018~present Chief Executive Officer, ORGANOIDSCIENCES Ltd.
2015-2020 Assistant Professor, School of Medicine, CHA University, Korea
2014-2015 Instructor, College of Medicine, Yonsei University, Korea
2007-2014 M.D, Ph.D, in Medicine, CHA University, Korea
1998-2004 B.S, in Life Science, Korea University, Korea

Current status and prospects of the organoid based regenerative medicine

Organoids derived from stem cells or organ-specific progenitors are self-organizable, self-renewable, and multicellular three-dimensional (3D) structures that can mimic the function and structure of the derived tissue. Due to such characteristics, organoids are attracting attention as an excellent ex vivo model for drug screening at the stage of drug development. In addition, since the applicability of organoids as therapeutics for tissue regeneration has been embossed, the development of various organoids-based regenerative medicine has been rapidly progressing, reaching the clinical trial stage. In this review, we give a general overview of organoids and describe current status and prospects of organoid-based regenerative medicine, focusing on organoid-based regenerative therapeutics currently under development including clinical trials.


BMB Rep. 2022 Dec 16;5808. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/36523211/