생화학분자생물학회입니다.
Entosis: the core mechanism and crosstalk with other cell death programs
작성자
Sung Eun Kim작성일자
2024-07-22조회수
888Sung Eun Kim( sek19@korea.ac.kr ) | ||
2022-present | Associate Professor, Department of Biosystems and Biomedical Sciences, Korea University, South Korea | |
2019-2022 | Assistant Professor, Department of Biosystems and Biomedical Sciences, Korea University, Seoul, South Korea | |
2016-2019 | Post-doctoral fellow, University of California, San Francisco, USA | |
2009-2016 | PhD, Cell and Development Biology (BCMB Allied Program), Weill Cornell Graduate School of Medical Sciences & Memorial Sloan Kettering Cancer, New York, USA | |
2008-2009 | Research technician, Korea University, South Korea | |
2006-2008 | MS, Animal Biotechnology and Genetic Engineering, Korea University, Seoul, South Korea | |
2002-2006 | BS, Biotechnology and Genetic Engineering, Korea University, Seoul, South Korea |
Entosis: the core mechanism and crosstalk with other cell death programs
Cell death pathways play critical roles in organism development and homeostasis as well as in the pathogenesis of various diseases. While studies over the last decade have elucidated numerous different forms of cell death that can eliminate cells in various contexts, how certain mechanisms impact physiology is still not well understood. Moreover, recent studies have shown that multiple forms cell death can occur in a cell population, with different forms of death eliminating individual cells. Here, we aim to describe the known molecular mechanisms of entosis, a non-apoptotic cell engulfment process, and discuss signaling mechanisms that control its induction as well as its possible crosstalk with other cell death mechanisms.
Exp Mol Med. 2024 Apr;56(4):870-876. doi: 10.1038/s12276-024-01227-w.
https://pubmed.ncbi.nlm.nih.gov/38565900/