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Neutrophils and neutrophil extracellular traps in oral health and disease

  • 작성자

    Tae Sung Kim
  • 작성일자

    2024-07-22
  • 조회수

    870
Tae Sung Kim( taesung.kim@nih.gov )
2023-presentSenior Researcher, National Institute of Dental and Craniofacial Research, National Institutes of Health, USA
2018-2023Postdoctoral Fellow, National Institute of Dental and Craniofacial Research, National Institutes of Health, USA
2017-2018Postdoctoral Fellow, Department of Microbiology, Infection Control Convergence Research Center, Chungnam National University School of Medicine, South Korea
2011-2017MS/PhD, Department of Microbiology, Department of Medical Science, Chungnam National University School of Medicine, South Korea

Neutrophils and neutrophil extracellular traps in oral health and disease

Neutrophils perform essential functions in antimicrobial defense and tissue maintenance at mucosal barriers. However, a dysregulated neutrophil response and, in particular, the excessive release of neutrophil extracellular traps (NETs) are implicated in the pathology of various diseases. In this review, we provide an overview of the basic concepts related to neutrophil functions, including NET formation, and discuss the mechanisms associated with NET activation and function in the context of the prevalent oral disease periodontitis.

Exp Mol Med. 2024 May;56(5):1055-1065. doi: 10.1038/s12276-024-01219-w.
https://pubmed.ncbi.nlm.nih.gov/38689085/